SCHEMBL30548748

SCHEMBL30548748

c1ccc(SC2CCCCC2)c(SC2CCCCC2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.44
MAOB P27338 4/20 0.44
ALDH1A1 P00352 5/20 0.42
MAPT P10636 3/20 0.42
HPGD P15428 2/20 0.42
PKM P14618 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
MC4R P32245 1/20 0.42
HSD17B10 Q99714 1/20 0.42
LMNA P02545 1/20 0.40
HIF1A Q16665 1/20 0.40
CETP P11597 1/20 0.39
VCP P55072 3/20 0.39
GAA P10253 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK1 P28482 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20495594 1.00 MAOA (0.44) MAOAMAOBALDH1A1MAPTHPGD
SCHEMBL30958574 0.89 ALDH1A1 (0.47) MAOAMAOBALDH1A1MAPTHPGD
SCHEMBL29242084 0.86 ALDH1A1 (0.42) MAOAMAOBALDH1A1MAPTHPGD
SCHEMBL5330982 0.85 MEN1 (0.43) MAOAMAOBALDH1A1MAPTHPGD
SCHEMBL8786030 0.85 MAPT (0.46) MAOAMAOBALDH1A1MAPTHPGD
SCHEMBL15271056 0.85 MEN1 (0.43) MAOAMAOBALDH1A1MAPTHPGD
SCHEMBL11292131 0.85 CA12 (0.39) MAOAMAOBALDH1A1MAPTHPGD
SCHEMBL202984 0.84 BCL2 (0.41) MAOAMAOBALDH1A1MAPTHPGD
SCHEMBL1147613 0.83 ALDH1A1 (0.56) ALDH1A1MAPTPKMALOX15HSD17B10
SCHEMBL15270965 0.83 MAOA (0.57) MAOAMAOBALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116657163-A Method for dithioating o-dihalogenated aromatic hydrocarbon 河南大学 2023-08-29 CN disclosed