SCHEMBL30548751

SCHEMBL30548751

Ic1cc2ccccc2cc1I

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.47
ALOX12 P18054 1/20 0.47
NQO2 P16083 1/20 0.43
ALDH1A1 P00352 6/20 0.41
HSD17B10 Q99714 5/20 0.41
CYP1A2 P05177 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
CYP3A4 P08684 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
HIF1A Q16665 3/20 0.39
CASP1 P29466 2/20 0.39
CASP7 P55210 2/20 0.39
HPGD P15428 2/20 0.39
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14800228 1.00 CYP2A6 (0.47) CYP2A6ALOX12NQO2ALDH1A1HSD17B10
SCHEMBL10013794 0.80 CYP2A6 (0.44) CYP2A6ALOX12NQO2ALDH1A1HSD17B10
SCHEMBL1672114 0.80 IDO1 (0.45) CYP2A6ALOX12NQO2ALDH1A1HSD17B10
SCHEMBL2966116 0.80 TRPM4 (0.46) NQO2ALDH1A1HSD17B10CYP1A2TDP1
SCHEMBL18683349 0.80 CYP2A6 (0.44) CYP2A6ALOX12NQO2ALDH1A1HSD17B10
SCHEMBL19180655 0.80 CYP2A6 (0.44) CYP2A6ALOX12NQO2ALDH1A1HSD17B10
SCHEMBL734973 0.80 CYP2A6 (0.44) CYP2A6ALOX12NQO2ALDH1A1HSD17B10
SCHEMBL26858453 0.80 CYP2A6 (0.35) CYP2A6ALOX12NQO2ALDH1A1HSD17B10
SCHEMBL15511865 0.78 ALDH1A1 (0.43) CYP2A6ALOX12NQO2ALDH1A1HSD17B10
SCHEMBL12952455 0.78 PTGS2 (0.47) CYP2A6ALDH1A1HSD17B10TDP1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024235507-A1 METHOD FOR PRODUCING A POLYMER, IN PARTICULAR FOR A MEMBRANE, POLYMER, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-11-21 WO disclosed
WO-2024160834-A1 METHOD FOR PRODUCING A POLYMER, IN PARTICULAR FOR A MEMBRANE, POLYMER, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-08-08 WO disclosed
CN-116657163-A Method for dithioating o-dihalogenated aromatic hydrocarbon 河南大学 2023-08-29 CN disclosed