Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871698 | 0.85 | POLB (0.36) | TDP1ALDH1A1POLB | |
| SCHEMBL5775122 | 0.81 | KDM4E (0.38) | L3MBTL1ALOX15KDM4ETDP1ALDH1A1 | |
| SCHEMBL29816028 | 0.81 | KDM4E (0.38) | L3MBTL1ALOX15KDM4ETDP1ALDH1A1 | |
| SCHEMBL30305190 | 0.80 | PARP1 (0.36) | KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL5779007 | 0.80 | PARP1 (0.36) | KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL27873839 | 0.79 | L3MBTL1 (0.39) | L3MBTL1KDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL26128039 | 0.77 | CA12 (0.48) | CA12CA9KDM4EALDH1A1POLB | |
| SCHEMBL27726338 | 0.75 | L3MBTL1 (0.44) | CA12CA9MAP2K1L3MBTL1ALOX15 | |
| SCHEMBL29911876 | 0.71 | TNKS2 (0.33) | L3MBTL1ALDH1A1MAPT | |
| SCHEMBL19142540 | 0.71 | TNKS2 (0.33) | L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023185811-A1 | NOVEL HETEROCYCLIC COMPOUND | 首药控股(北京)股份有限公司 | 2023-10-05 | — | — | WO | disclosed |