SCHEMBL30549409

SCHEMBL30549409

N#C/C(=C\c1ccc2[nH]ccc2c1)C(=O)c1ccc(O)c(O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 14/20 0.70
ERBB2 P04626 9/20 0.70
ALDH1A1 P00352 5/20 0.70
MAPT P10636 5/20 0.70
KDM4E B2RXH2 4/20 0.70
MEN1 O00255 4/20 0.70
CYP1A2 P05177 4/20 0.70
HPGD P15428 4/20 0.70
KMT2A Q03164 4/20 0.70
HSD17B10 Q99714 4/20 0.70
USP2 O75604 3/20 0.70
POLB P06746 3/20 0.70
CYP3A4 P08684 3/20 0.70
ALOX15 P16050 3/20 0.70
ALOX12 P18054 3/20 0.70
MAPK1 P28482 3/20 0.70
RECQL P46063 3/20 0.70
BLM P54132 3/20 0.70
PMP22 Q01453 3/20 0.70
HIF1A Q16665 3/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6213665 1.00 EGFR (0.70) EGFRERBB2ALDH1A1MAPTKDM4E
SCHEMBL6213658 1.00 EGFR (0.70) EGFRERBB2ALDH1A1MAPTKDM4E
SCHEMBL6213656 1.00 EGFR (0.70) EGFRERBB2ALDH1A1MAPTKDM4E
SCHEMBL29429711 0.84 EGFR (1.00) EGFRERBB2ALDH1A1MAPTKDM4E
SCHEMBL2678765 0.84 EGFR (1.00) EGFRERBB2ALDH1A1MAPTKDM4E
SCHEMBL2678764 0.84 EGFR (1.00) EGFRERBB2ALDH1A1MAPTKDM4E
SCHEMBL2678762 0.84 EGFR (1.00) EGFRERBB2ALDH1A1MAPTKDM4E
SCHEMBL17480115 0.80 ALDH1A1 (0.67) EGFRALDH1A1MAPTKDM4EHPGD
SCHEMBL16627347 0.80 ALDH1A1 (0.67) EGFRALDH1A1MAPTKDM4EHPGD
SCHEMBL14682582 0.79 MAPT (0.74) EGFRERBB2ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117965156-A Preparation method of hydrophobic in-situ generation propping agent 凯泽未来(无锡)数字智能科技有限公司 2024-05-03 CN disclosed
CN-116556257-A Tidal simulation device and method 广东工业大学 2023-08-08 CN disclosed