Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 13/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 9/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054 | 0.87 | LTB4R2 (0.49) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL2785 | 0.87 | LTB4R2 (0.63) | LTB4R2AGTR1 | |
| SCHEMBL2786 | 0.87 | LTB4R2 (0.63) | LTB4R2AGTR1 | |
| SCHEMBL2971 | 0.77 | BDKRB1 (0.36) | LTB4R2AGTR1 | |
| SCHEMBL2722 | 0.77 | BDKRB1 (0.36) | LTB4R2AGTR1 | |
| SCHEMBL2395 | 0.72 | LTB4R2 (0.75) | LTB4R2AGTR1 | |
| SCHEMBL2394 | 0.72 | LTB4R2 (0.75) | LTB4R2AGTR1 | |
| SCHEMBL8475874 | 0.69 | LTB4R2 (0.71) | LTB4R2AGTR1 | |
| SCHEMBL2127 | 0.68 | SCN1A (0.50) | LTB4R2 | |
| SCHEMBL3202 | 0.67 | SCN1A (0.51) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |