SCHEMBL31362881

SCHEMBL31362881

C[C@@H](CC(F)Cn1ccc2cc(-c3ncc(C(F)(F)F)cn3)ccc2c1=O)Nc1cnn(COCC[Si](C)(C)C)c(=O)c1C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TIPARP Q7Z3E1 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31362913 0.90 TIPARP (0.43) TIPARP
SCHEMBL30550644 0.89 TIPARP (0.45) TIPARP
SCHEMBL25320156 0.89 TIPARP (0.45) TIPARP
SCHEMBL25320149 0.89 TIPARP (0.45) TIPARP
SCHEMBL31362994 0.85 TIPARP (0.41) TIPARP
SCHEMBL31363024 0.84 TIPARP (0.41) TIPARP
SCHEMBL31362979 0.84 TIPARP (0.36) TIPARP
SCHEMBL31362942 0.84 TIPARP (0.36) TIPARP
SCHEMBL25323292 0.81 TIPARP (0.41) TIPARP
SCHEMBL25323288 0.81 TIPARP (0.41) TIPARP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024663-A1 PARP7 INHIBITORS GILEAD SCIENCES, INC. (US) 2025-01-30 — — WO disclosed
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