SCHEMBL30550745

SCHEMBL30550745

CC#C[C@@H](CCCn1ccc2cc(-c3ncc(C(F)(F)F)cn3)c(F)c(F)c2c1=O)N[S@+]([O-])C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TIPARP Q7Z3E1 6/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25322309 1.00 TIPARP (0.35) TIPARP
SCHEMBL25322315 1.00 TIPARP (0.35) TIPARP
SCHEMBL30550595 0.83 TIPARP (0.37) TIPARP
SCHEMBL25320708 0.83 TIPARP (0.37) TIPARP
SCHEMBL25320713 0.83 TIPARP (0.37) TIPARP
SCHEMBL30550810 0.81 TIPARP (0.52) TIPARP
SCHEMBL25320554 0.81 TIPARP (0.52) TIPARP
SCHEMBL25320551 0.81 TIPARP (0.52) TIPARP
SCHEMBL31058433 0.78 LMNA (0.40) TIPARP
SCHEMBL25898093 0.77 LMNA (0.41) TIPARP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4469448-A1 PARP7 INHIBITORS GILEAD SCIENCES, INC. (US) 2024-12-04 — — EP disclosed
CN-118591537-A PARP7 inhibitors 吉利德科学公司 2024-09-03 — — CN disclosed
WO-2023147418-A1 PARP7 INHIBITORS GILEAD SCIENCES, INC. (US) 2023-08-03 — — WO disclosed
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