Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.39 |
| ▸ | HTR2A | P28223 | 19/20 | 0.39 |
| ▸ | DRD3 | P35462 | 19/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322264 | 1.00 | DRD2 (0.39) | DRD2HTR2ADRD3MTNR1B | |
| SCHEMBL25321990 | 0.96 | DRD2 (0.41) | DRD2HTR2ADRD3MTNR1B | |
| SCHEMBL25321987 | 0.96 | DRD2 (0.41) | DRD2HTR2ADRD3MTNR1B | |
| SCHEMBL25321780 | 0.92 | DRD2 (0.39) | DRD2HTR2ADRD3MTNR1B | |
| SCHEMBL30551252 | 0.92 | DRD2 (0.39) | DRD2HTR2ADRD3MTNR1B | |
| SCHEMBL30551527 | 0.86 | NR3C1 (0.33) | — | |
| SCHEMBL25322215 | 0.86 | NR3C1 (0.33) | — | |
| SCHEMBL25322311 | 0.81 | NR3C1 (0.35) | — | |
| SCHEMBL25322314 | 0.81 | NR3C1 (0.35) | — | |
| SCHEMBL25323678 | 0.79 | NR3C1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469455-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |