Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.30 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25323291 | 1.00 | TRPV1 (0.36) | TRPV1SLC16A3SLC16A1RBP4PRMT5 | |
| SCHEMBL25920777 | 0.96 | TRPV1 (0.37) | TRPV1RBP4PRMT5WDR77 | |
| SCHEMBL25324948 | 0.96 | TRPV1 (0.37) | TRPV1RBP4PRMT5WDR77 | |
| SCHEMBL25324944 | 0.96 | TRPV1 (0.37) | TRPV1RBP4PRMT5WDR77 | |
| SCHEMBL25324708 | 0.78 | KDM1A (0.39) | PRMT5WDR77 | |
| SCHEMBL25920778 | 0.78 | TRPV1 (0.39) | TRPV1PRMT5WDR77 | |
| SCHEMBL25322685 | 0.78 | TRPV1 (0.39) | TRPV1PRMT5WDR77 | |
| SCHEMBL25322681 | 0.78 | TRPV1 (0.39) | TRPV1PRMT5WDR77 | |
| SCHEMBL25322264 | 0.77 | DRD2 (0.39) | — | |
| SCHEMBL30551527 | 0.77 | NR3C1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469455-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |