SCHEMBL305519

SCHEMBL305519

CN(C)C(=O)CSC(=S)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.51
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
ALDH1A1 P00352 4/20 0.46
MAPT P10636 1/20 0.46
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
HSP90AA1 P07900 2/20 0.42
HSP90AB1 P08238 1/20 0.42
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4437686 0.83 ALDH1A1 (0.43) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL162936 0.80 ALDH1A1 (0.52) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL4832150 0.78 ALDH1A1 (0.50) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL4231270 0.77 MAPT (0.49) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL3048238 0.76 TSHR (0.46) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL22204622 0.75 HDAC3 (0.44) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL4828712 0.75 CA2 (0.47) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL23690534 0.74 KMT2A (0.40) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL22204623 0.73 HDAC3 (0.43) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL11525933 0.72 SMN1; SMN2 (0.71) KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150240103-A1 COMPOSITIONS FOR HIGH SPEED PRINTING OF CONDUCTIVE MATERIALS FOR ELECTRONIC CIRCUITRY TYPE APPLICATIONS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY 2015-08-27 US disclosed
US-8093180-B2 curing the curable amphiphilic monomer mixture by free radical polymerization in water solvent, impregnating with cationic brightener, improve functionality; produced at high speeds, low cost, safety, no pollution; use in separation, concentration and purification of gasses, liquids and mixtures FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2012-01-10 US disclosed
US-8084558-B2 Preparation of transition metal nanoparticles and surfaces modified with (co)polymers synthesized by RAFT UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-12-27 US disclosed
US-8034444-B2 Porous membranes and recording media comprising same FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2011-10-11 US disclosed
US-20110163478-A1 Porous Membrane and Recording Media Comprising Same FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2011-07-07 US disclosed
EP-2051861-B1 POROUS MEMBRANE AND ITS METHOD OF MANUFACTURE FUJIFILM MFG EUROPE BV (NL) 2011-03-23 EP disclosed
US-7910520-B2 Porous membrane and recording medium comprising same FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2011-03-22 US disclosed
EP-2052039-B1 COMPOSITIONS FOR POROUS MEMBRANES AND RECORDING MEDIA FUJIFILM MFG EUROPE BV (NL) 2010-07-14 EP disclosed
US-20100140828-A1 Porous Membrane and Recording Medium Comprising Same FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2010-06-10 US disclosed
US-7704573-B2 Porous membrane and recording medium comprising same FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2010-04-27 US disclosed
WO-2007018425-A1 POROUS MEMBRANE AND RECORDING MEDIUM COMPRISING SAME FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2007-02-15 WO disclosed
WO-2007018421-A1 POROUS MEMBRANE AND RECORDING MEDIUM COMPRISING SAME FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2007-02-15 WO disclosed
US-7138468-B2 Preparation of transition metal nanoparticles and surfaces modified with (CO)polymers synthesized by RAFT UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2006-11-21 US disclosed
US-20060111531-A1 Chain transfer agents for RAFT polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI 2006-05-25 US disclosed
US-20060111532-A1 Chain transfer agents for RAFT polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI 2006-05-25 US disclosed
US-6855840-B2 Chain transfer agents for raft polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2005-02-15 US disclosed
US-20030199653-A1 Preparation of transition metal nanoparticles and surfaces modified with (co)polymers synthesized by RAFT UNIVERSITY OF SOUTHERN MISSISSIPPI 2003-10-23 US disclosed
US-20030195310-A1 Chain transfer agents for raft polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI 2003-10-16 US disclosed
US-20030191262-A1 Chain transfer agents for raft polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI 2003-10-09 US disclosed
WO-2003066685-A2 CHAIN TRANSFER AGENTS FOR RAFT POLYMERIZATION IN AQUEOUS MEDIA UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195310-A1 Chain transfer agents for raft polymerization in aqueous media TRRAP, NEFM, TMT1A KMT2A 4171/4885NPC1 2755/4885RAB9A 2906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.