Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 11/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 4/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25325358 | 1.00 | PDE2A (0.35) | PDE2AEPHX2ENPP2ATXN2MGLL | |
| SCHEMBL25325783 | 0.89 | PDE2A (0.41) | PDE2AEPHX2ENPP2ATXN2MGLL | |
| SCHEMBL25325772 | 0.85 | RIPK1 (0.33) | MGLL | |
| SCHEMBL25325639 | 0.81 | F2R (0.33) | EPHX2ENPP2ATXN2MGLL | |
| SCHEMBL25325039 | 0.80 | MGLL (0.40) | PDE2AMGLL | |
| SCHEMBL25325994 | 0.80 | MGLL (0.34) | MGLL | |
| SCHEMBL25324716 | 0.79 | MGLL (0.31) | MGLL | |
| SCHEMBL25324592 | 0.78 | MGLL (0.32) | MGLL | |
| SCHEMBL25323304 | 0.77 | MGLL (0.39) | MGLL | |
| SCHEMBL30553247 | 0.77 | MGLL (0.39) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |