Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326481 | 1.00 | MGLL (0.39) | MGLLABHD6SMYD3ADORA2BADORA2A | |
| SCHEMBL25326182 | 0.88 | MGLL (0.39) | MGLLADORA2B | |
| SCHEMBL30553182 | 0.88 | MGLL (0.39) | MGLLADORA2B | |
| SCHEMBL30553208 | 0.87 | MGLL (0.42) | MGLLADORA2B | |
| SCHEMBL25324678 | 0.87 | MGLL (0.42) | MGLLADORA2B | |
| SCHEMBL25325192 | 0.85 | MGLL (0.37) | MGLL | |
| SCHEMBL30553306 | 0.85 | MGLL (0.37) | MGLL | |
| SCHEMBL25327463 | 0.84 | HDAC4 (0.41) | MGLLABHD6SMYD3 | |
| SCHEMBL30553258 | 0.84 | HDAC4 (0.41) | MGLLABHD6SMYD3 | |
| SCHEMBL25324763 | 0.83 | MGLL (0.41) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |