Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25325192 | 1.00 | MGLL (0.37) | MGLLGPBAR1 | |
| SCHEMBL25326033 | 0.87 | MGLL (0.37) | MGLL | |
| SCHEMBL25326672 | 0.87 | CCR5 (0.38) | MGLLGPBAR1 | |
| SCHEMBL25325560 | 0.86 | MGLL (0.38) | MGLLGPBAR1 | |
| SCHEMBL30553145 | 0.85 | MGLL (0.39) | MGLL | |
| SCHEMBL30553182 | 0.85 | MGLL (0.39) | MGLL | |
| SCHEMBL25326481 | 0.85 | MGLL (0.39) | MGLL | |
| SCHEMBL25326182 | 0.85 | MGLL (0.39) | MGLL | |
| SCHEMBL25324987 | 0.84 | OPRM1 (0.35) | MGLL | |
| SCHEMBL25328128 | 0.83 | GPBAR1 (0.37) | MGLLGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |