Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25325643 | 1.00 | MGLL (0.43) | MGLLCYP11B1CYP11B2GPR119 | |
| SCHEMBL25326309 | 0.93 | MGLL (0.43) | MGLLCYP11B1CYP11B2GPR119 | |
| SCHEMBL30699852 | 0.92 | MGLL (0.42) | MGLL | |
| SCHEMBL25324927 | 0.87 | MGLL (0.43) | MGLL | |
| SCHEMBL30700116 | 0.86 | MGLL (0.42) | MGLLGPR119 | |
| SCHEMBL25323946 | 0.84 | MGLL (0.42) | MGLLCYP11B1CYP11B2GPR119 | |
| SCHEMBL25324898 | 0.83 | MGLL (0.39) | MGLL | |
| SCHEMBL25326643 | 0.80 | MGLL (0.37) | MGLL | |
| SCHEMBL25326232 | 0.80 | MGLL (0.44) | MGLLCYP11B1CYP11B2 | |
| SCHEMBL30553221 | 0.80 | MGLL (0.44) | MGLLCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | claimed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | claimed |
| EP-4469446-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |