Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3052036 | 0.79 | DHCR7 (0.80) | DHCR7ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL3054533 | 0.77 | DHCR7 (0.70) | DHCR7ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL3052193 | 0.74 | SIGMAR1 (0.42) | DHCR7ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL2918653 | 0.73 | SIGMAR1 (0.63) | ALDH1A1KDM4EMAPTSIGMAR1MEN1 | |
| SCHEMBL3041403 | 0.73 | DHCR7 (0.42) | DHCR7ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL3046693 | 0.73 | CA2 (0.47) | DHCR7ALDH1A1KDM4EMAPTSIGMAR1 | |
| SCHEMBL3050133 | 0.72 | DHCR7 (0.55) | DHCR7ALDH1A1KDM4ESIGMAR1TDP1 | |
| SCHEMBL3051837 | 0.71 | DHCR7 (0.67) | DHCR7ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL3064349 | 0.71 | DHCR7 (0.67) | DHCR7ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL3058753 | 0.71 | DHCR7 (0.53) | DHCR7ALDH1A1KDM4ESIGMAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | DHCR7 421/4885ALDH1A1 1517/4885KDM4E 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.