Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.36 |
| ▸ | GSK3A | P49840 | 4/20 | 0.36 |
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | PRKACA | P17612 | 3/20 | 0.36 |
| ▸ | PRKX | P51817 | 3/20 | 0.36 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20920136 | 1.00 | MAPK1 (0.39) | MAPK1MAPK3PKMHTTALDH1A1 | |
| SCHEMBL20920137 | 1.00 | MAPK1 (0.39) | MAPK1MAPK3PKMHTTALDH1A1 | |
| SCHEMBL22284303 | 0.93 | ROCK2 (0.42) | MAPK1MAPK3PKMHTTALDH1A1 | |
| SCHEMBL30554287 | 0.93 | ROCK2 (0.42) | MAPK1MAPK3PKMHTTALDH1A1 | |
| SCHEMBL22284300 | 0.93 | ROCK2 (0.42) | MAPK1MAPK3PKMHTTALDH1A1 | |
| SCHEMBL22284153 | 0.93 | MAPK1 (0.40) | MAPK1MAPK3PKMHTTROCK1 | |
| SCHEMBL30554317 | 0.93 | MAPK1 (0.40) | MAPK1MAPK3PKMHTTROCK1 | |
| SCHEMBL22284155 | 0.93 | MAPK1 (0.40) | MAPK1MAPK3PKMHTTROCK1 | |
| SCHEMBL22284238 | 0.92 | MAPK1 (0.39) | MAPK1MAPK3PKMHTTROCK1 | |
| SCHEMBL22284237 | 0.92 | MAPK1 (0.39) | MAPK1MAPK3PKMHTTROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112020357-B | Salt of indazolyl-containing tricyclic derivative and crystal form thereof | 上海翰森生物医药科技有限公司 | 2023-08-29 | — | — | CN | disclosed |