Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20916954 | 1.00 | SRC (0.34) | SRCBRAFKDRADORA2AADORA1 | |
| SCHEMBL30084116 | 0.86 | PTGER1 (0.38) | SRCBRAFKDRADORA2AADORA1 | |
| SCHEMBL30084121 | 0.86 | PTGER1 (0.42) | SRCBRAFKDRADORA2AADORA1 | |
| SCHEMBL173515 | 0.86 | PTGER1 (0.38) | SRCBRAFKDRADORA2AADORA1 | |
| SCHEMBL22284230 | 0.84 | ADORA2A (0.36) | ADORA2AMAPK14 | |
| SCHEMBL16619937 | 0.83 | ALDH1A1 (0.36) | ADORA2AADORA1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2732363 | 0.81 | DCLK1 (0.40) | MKNK1NOTUML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL2733380 | 0.81 | MKNK1 (0.33) | MKNK1NOTUML3MBTL1KIF11CYP11B1 | |
| SCHEMBL30084130 | 0.81 | PTGER1 (0.38) | BRAFMKNK1NOTUML3MBTL1ALDH1A1 | |
| SCHEMBL20920119 | 0.79 | L3MBTL1 (0.41) | L3MBTL1CYP11B1CYP11B2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112020357-B | Salt of indazolyl-containing tricyclic derivative and crystal form thereof | 上海翰森生物医药科技有限公司 | 2023-08-29 | — | — | CN | disclosed |