Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 17/20 | 0.53 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | PRKX | P51817 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20931371 | 1.00 | MAPK1 (0.53) | MAPK1MAPK3ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL20916856 | 1.00 | MAPK1 (0.53) | MAPK1MAPK3ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL20916811 | 1.00 | MAPK1 (0.53) | MAPK1MAPK3ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL30554347 | 1.00 | MAPK1 (0.53) | MAPK1MAPK3ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL22284173 | 0.92 | MAPK1 (0.55) | MAPK1MAPK3ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL30554358 | 0.92 | MAPK1 (0.55) | MAPK1MAPK3ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL20931683 | 0.92 | MAPK1 (0.55) | MAPK1MAPK3ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL20931318 | 0.91 | MAPK1 (0.51) | MAPK1MAPK3CYP3A4 | |
| SCHEMBL22284179 | 0.91 | MAPK1 (0.51) | MAPK1MAPK3CYP3A4 | |
| SCHEMBL22284151 | 0.91 | MAPK1 (0.54) | MAPK1MAPK3ROCK2RPS6KA5CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112020357-B | Salt of indazolyl-containing tricyclic derivative and crystal form thereof | 上海翰森生物医药科技有限公司 | 2023-08-29 | — | — | CN | disclosed |