Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 16/20 | 0.55 |
| ▸ | MAPK3 | P27361 | 7/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PRKX | P51817 | 2/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.41 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.41 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | SGK2 | Q9HBY8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20931683 | 1.00 | MAPK1 (0.55) | MAPK1MAPK3LRRK2ROCK2ROCK1 | |
| SCHEMBL22284173 | 1.00 | MAPK1 (0.55) | MAPK1MAPK3LRRK2ROCK2ROCK1 | |
| SCHEMBL22284151 | 0.92 | MAPK1 (0.54) | MAPK1MAPK3LRRK2ROCK2ROCK1 | |
| SCHEMBL20931754 | 0.92 | MAPK1 (0.54) | MAPK1MAPK3LRRK2ROCK2ROCK1 | |
| SCHEMBL30554347 | 0.92 | MAPK1 (0.53) | MAPK1MAPK3ROCK2ROCK1PRKG1 | |
| SCHEMBL20916856 | 0.92 | MAPK1 (0.53) | MAPK1MAPK3ROCK2ROCK1PRKG1 | |
| SCHEMBL30554352 | 0.92 | MAPK1 (0.53) | MAPK1MAPK3ROCK2ROCK1PRKG1 | |
| SCHEMBL20931371 | 0.92 | MAPK1 (0.53) | MAPK1MAPK3ROCK2ROCK1PRKG1 | |
| SCHEMBL20916811 | 0.92 | MAPK1 (0.53) | MAPK1MAPK3ROCK2ROCK1PRKG1 | |
| SCHEMBL20931844 | 0.91 | MAPK1 (0.54) | MAPK1MAPK3ROCK2ROCK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112020357-B | Salt of indazolyl-containing tricyclic derivative and crystal form thereof | 上海翰森生物医药科技有限公司 | 2023-08-29 | — | — | CN | disclosed |