Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.65 |
| ▸ | CAMK2D | Q13557 | 6/20 | 0.64 |
| ▸ | CDK4 | P11802 | 4/20 | 0.63 |
| ▸ | CCND3 | P30281 | 3/20 | 0.63 |
| ▸ | GSK3B | P49841 | 3/20 | 0.63 |
| ▸ | PRKCA | P17252 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | BCR | P11274 | 2/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 4/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25980185 | 1.00 | PLK1 (0.65) | PLK1CAMK2DCDK4CCND3GSK3B | |
| SCHEMBL2956376 | 0.87 | PLK1 (0.68) | PLK1CAMK2DCDK4CCND3GSK3B | |
| SCHEMBL25335754 | 0.84 | SYK (0.61) | PLK1CAMK2DGSK3BPRKCAABL1 | |
| SCHEMBL31119111 | 0.84 | SYK (0.61) | PLK1CAMK2DGSK3BPRKCAABL1 | |
| SCHEMBL2946515 | 0.83 | PLK1 (0.77) | PLK1CAMK2DCDK4CCND3GSK3B | |
| SCHEMBL4732841 | 0.80 | PLK1 (1.00) | PLK1CAMK2DCDK4CCND3GSK3B | |
| SCHEMBL30335652 | 0.80 | PLK1 (0.60) | PLK1CAMK2DCDK4CCND3GSK3B | |
| SCHEMBL30554576 | 0.78 | PLK1 (0.56) | PLK1CAMK2DCDK4CCND3GSK3B | |
| SCHEMBL30554577 | 0.78 | PLK1 (0.56) | PLK1CAMK2DCDK4CCND3GSK3B | |
| SCHEMBL25981630 | 0.78 | PLK1 (0.56) | PLK1CAMK2DCDK4CCND3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12371408-B2 | Aryl hydrocarbon receptor agonists and uses thereof | NEXYS THERAPEUTICS, INC. (US) | 2025-07-29 | — | — | US | disclosed |
| US-12168646-B2 | Aryl hydrocarbon receptor agonists and uses thereof | NEXYS THERAPEUTICS, INC. (US) | 2024-12-17 | — | — | US | disclosed |
| EP-4472953-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | Nexys Therapeutics, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| US-20240279185-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | US | disclosed |
| US-20240208913-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371408-B2 | Aryl hydrocarbon receptor agonists and uses thereof | AHR, ARNT, NR1H2 | PLK1 4810/4885CAMK2D 1708/4885CDK4 3495/4885 |
| US-20240279185-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | AHR, ARNT, NR1H2 | PLK1 4810/4885CAMK2D 1708/4885CDK4 3495/4885 |
| US-12168646-B2 | Aryl hydrocarbon receptor agonists and uses thereof | AHR, ARNT, NR1H2 | PLK1 4810/4885CAMK2D 1708/4885CDK4 3495/4885 |
| US-20240208913-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | AHR, ARNT, NR1H2 | PLK1 4810/4885CAMK2D 1708/4885CDK4 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.