Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.60 |
| ▸ | CDK4 | P11802 | 2/20 | 0.56 |
| ▸ | CCND3 | P30281 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.55 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.55 |
| ▸ | CAMK2D | Q13557 | 6/20 | 0.53 |
| ▸ | PRKCA | P17252 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956376 | 0.81 | PLK1 (0.68) | PLK1CDK4CCND3GSK3BCAMK2D | |
| SCHEMBL15533101 | 0.81 | CCNB2 (0.55) | CDK4CCND3GSK3BCCNB2CDK1 | |
| SCHEMBL25980185 | 0.80 | PLK1 (0.65) | PLK1CDK4CCND3GSK3BCAMK2D | |
| SCHEMBL30554577 | 0.80 | PLK1 (0.56) | PLK1CDK4CCND3GSK3BCAMK2D | |
| SCHEMBL30554576 | 0.80 | PLK1 (0.56) | PLK1CDK4CCND3GSK3BCAMK2D | |
| SCHEMBL30554522 | 0.80 | PLK1 (0.65) | PLK1CDK4CCND3GSK3BCAMK2D | |
| SCHEMBL25981630 | 0.80 | PLK1 (0.56) | PLK1CDK4CCND3GSK3BCAMK2D | |
| SCHEMBL2946515 | 0.80 | PLK1 (0.77) | PLK1CDK4CCND3GSK3BCAMK2D | |
| SCHEMBL14651462 | 0.78 | PLK1 (0.84) | PLK1CDK4GSK3BCDK1CCNB1 | |
| SCHEMBL15533961 | 0.78 | CAMKK2 (0.53) | GSK3BCCNB2CDK1RETCCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230152314-A1 | LIPOCALIN-2 ASSAY FOR INTESTINAL ADAPTATION | THE JOHNS HOPKINS UNIVERSITY | 2023-05-18 | — | — | US | disclosed |