Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956400 | 0.80 | TAAR1 (0.39) | SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL8418210 | 0.77 | L3MBTL1 (0.47) | KDM1AMAOASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL29712485 | 0.76 | L3MBTL1 (0.46) | KDM1AMAOASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL696401 | 0.76 | L3MBTL1 (0.46) | KDM1AMAOASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL5045894 | 0.76 | L3MBTL1 (0.46) | KDM1AMAOASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL24685480 | 0.76 | L3MBTL1 (0.46) | KDM1AMAOASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL16892228 | 0.76 | L3MBTL1 (0.46) | KDM1AMAOASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL2426746 | 0.76 | CD274 (0.49) | KDM1AMAOASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL178447 | 0.76 | L3MBTL1 (0.46) | KDM1AMAOASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL30590652 | 0.76 | L3MBTL1 (0.46) | KDM1AMAOASMN1; SMN2MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4476229-A1 | INDUCERS OF KLF2 AND METHODS OF USE THEREOF | Riparian Pharmaceuticals, Inc. (US) | 2024-12-18 | — | — | EP | disclosed |
| CN-118974057-A | KLF2 inducers and methods of use thereof | 里帕里安制药股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| WO-2023150374-A1 | INDUCERS OF KLF2 AND METHODS OF USE THEREOF | RIPARIAN PHARMACEUTICALS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |