SCHEMBL305563

SCHEMBL305563

CC(O)c1ccccc1C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.52
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
HSD17B10 Q99714 1/20 0.48
METAP2 P50579 1/20 0.45
HTT P42858 1/20 0.45
BCAT2 O15382 1/20 0.44
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
GAA P10253 2/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
CTNNB1 P35222 1/20 0.40
SIRT1 Q96EB6 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
CES2 O00748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31400625 1.00 IRAK4 (0.52) IRAK4KDM4EALDH1A1MAPTHPGD
SCHEMBL31632660 0.87 IRAK4 (0.55) IRAK4KDM4EALDH1A1MAPTHPGD
SCHEMBL105262 0.87 IRAK4 (0.55) IRAK4KDM4EALDH1A1MAPTHPGD
Hydrochloric Acid SCHEMBL28294057 0.85 IRAK4 (0.53) IRAK4KDM4EALDH1A1MAPTHPGD
SCHEMBL9783644 0.85 IRAK4 (0.53) IRAK4KDM4EALDH1A1MAPTHPGD
Hydrochloric Acid SCHEMBL7849679 0.85 IRAK4 (0.53) IRAK4KDM4EALDH1A1MAPTHPGD
SCHEMBL3183101 0.84 IRAK4 (0.49) IRAK4KDM4EALDH1A1MAPTHPGD
SCHEMBL731619 0.83 IRAK4 (0.52) IRAK4KDM4EALDH1A1MAPTHPGD
SCHEMBL2335765 0.82 IRAK4 (0.43) IRAK4KDM4EALDH1A1MAPTHPGD
SCHEMBL15163057 0.82 IRAK4 (0.47) IRAK4KDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6458865-B2 FOR DENTAL RESTORATION MATERIAL CURATORS OF THE UNIVERSITY OF MISSOURI 2002-10-01 US claimed
US-10031394-B2 Electrophoretic particle, electrophoretic particle dispersion liquid, display medium, and display device E INK CORPORATION (US) 2018-07-24 US disclosed
CN-103978202-B biological detection sheet and manufacturing method thereof 智超虹研发有限公司 2017-04-12 CN disclosed
CN-105492556-A Linerless sheeting article 3M INNOVATIVE PROPERTIES CO 2016-04-13 CN disclosed
US-9152005-B2 Particle dispersion for display, display medium, and display device FUJI XEROX CO., LTD. (JP) 2015-10-06 US disclosed
CN-104352492-A Long-chain fatty acyl elongase inhibitor comprising arylsulfonyl derivative as active ingredient MSD KK 2015-02-18 CN disclosed
CN-103978202-A Nano silver wire composition for biological detection sheet, biological detection sheet and manufacturing method thereof CUBIC RES CO LTD K 2014-08-13 CN disclosed
US-8778219-B2 Ionic liquids for separation of olefin-paraffin mixtures UT-BATTELLE, LLC (US) 2014-07-15 US disclosed
EP-2734497-A1 INDANE DIMERS FOR USE IN THE TREATMENT OF AUTOIMMUNE INFLAMMATORY DISEASE Venantius Limited (IE) 2014-05-28 EP disclosed
US-8717282-B2 White particles for display, particle dispersion for display, display medium and display device FUJI XEROX CO., LTD. (JP) 2014-05-06 US disclosed
CN-1308570-A Coated abrasive article MINNESOTA MINING & MFG (US) 2001-08-15 CN disclosed
CN-1259085-A Bonding system in an ink jet printer pen and method for providing the same MINNESOTA MINING & MFG (US) 2000-07-05 CN disclosed
CN-1252137-A Ternary photoinitiator system for curing of epoxy/polyol resin compositions MINNESOTA MINING & MFG (US) 2000-05-03 CN disclosed
CN-1040760-C Unsymmetrieal aryl phosphite CIBA GEIGY AG (CH) 1998-11-18 CN disclosed
CN-1181102-A Melt-flowable materials and method of sealing surfaces MINNESOTA MINING & MFG (US) 1998-05-06 CN disclosed
US-5724629-A Liquid developer monitoring device, liquid developer controlling system, and image forming apparatus using same MINOLTA CO., LTD. (JP) 1998-03-03 US disclosed
US-5689779-A Liquid developer and developing method and developing apparatus using same MINOLTA CO., LTD. (JP) 1997-11-18 US disclosed
CN-1134715-A Melt flowable material and method of surface sealing MINNESOTA MINING & MFG (US) 1996-10-30 CN disclosed
CN-1065273-A Asymmetric aryl phosphite CIBA GEIGY AG (CH) 1992-10-14 CN disclosed
EP-0357467-A1 Non-ionic tri-iodobenzene compounds, and contrast agents containing same GUERBET S.A. (FR) 1990-03-07 EP disclosed