Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3683840 | 0.98 | IRAK4 (0.50) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL105262 | 0.87 | IRAK4 (0.55) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL31632660 | 0.87 | IRAK4 (0.55) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL15163057 | 0.86 | IRAK4 (0.47) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9783644 | 0.85 | IRAK4 (0.53) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL28294057 | 0.85 | IRAK4 (0.53) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL7849679 | 0.85 | IRAK4 (0.53) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL1449566 | 0.83 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL10726252 | 0.83 | IRAK4 (0.43) | IRAK4KDM4EALDH1A1TSHRCYP1A2 | |
| SCHEMBL28814411 | 0.83 | IRAK4 (0.43) | IRAK4KDM4EALDH1A1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1048214-A | The preparation method of new anti-arrhythmic II | HAESSLE AB (SE) | 1991-01-02 | — | — | CN | claimed |
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | PURDUE RESEARCH FOUNDATION | 2024-07-18 | — | — | US | disclosed |
| CN-117460507-A | Compound targeting fibroblast activation protein and method of use thereof | 普渡研究基金会 | 2024-01-26 | — | — | CN | disclosed |
| EP-4308110-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | Purdue Research Foundation (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-111012918-B | Cholesterol biguanide conjugate with anti-tumor and carrier effects and application of salt thereof in microparticle administration preparation | 郑州大学 | 2023-04-07 | — | — | CN | disclosed |
| WO-2022197567-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2022-09-22 | — | — | WO | disclosed |
| CN-111012918-A | Cholesterol biguanide conjugate with anti-tumor and carrier effects and application of salt thereof in microparticle administration preparation | 郑州大学 | 2020-04-17 | — | — | CN | disclosed |
| US-8778219-B2 | Ionic liquids for separation of olefin-paraffin mixtures | UT-BATTELLE, LLC (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130338389-A1 | IONIC LIQUIDS FOR SEPARATION OF OLEFIN-PARAFFIN MIXTURES | UT-BATTELLE, LLC (US) | 2013-12-19 | — | — | US | disclosed |
| US-8535560-B2 | Ionic liquids for separation of olefin-paraffin mixtures | UT-BATTELLE, LLC (US) | 2013-09-17 | — | — | US | disclosed |
| US-8138209-B2 | Substituted picolinamides as MAO-B inhibitors useful for treating obesity | JENRIN DISCOVERY, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| WO-2011008664-A2 | IONIC LIQUIDS FOR SEPARATION OF OLEFIN-PARAFFIN MIXTURES | UT-BATTELLE, LLC (US) | 2011-01-20 | — | — | WO | disclosed |
| US-20110015461-A1 | Ionic Liquids for Separation of Olefin-Paraffin Mixtures | UT-BATTELLE, LLC (US) | 2011-01-20 | — | — | US | disclosed |
| US-7655396-B1 | Methods for detecting receptor modulator activity | ALLERGAN, INC. (US) | 2010-02-02 | — | — | US | disclosed |
| WO-2007008963-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2007-01-18 | — | — | WO | disclosed |
| US-20070015734-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2007-01-18 | — | — | US | disclosed |
| US-5010108-A | Treatment of gastrointestinal disorders | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 1991-04-23 | — | — | US | disclosed |
| CN-1048214-A | The preparation method of new anti-arrhythmic II | HAESSLE AB (SE) | 1991-01-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338389-A1 | IONIC LIQUIDS FOR SEPARATION OF OLEFIN-PARAFFIN MIXTURES | POU2F1, POU2F2, POF1B | IRAK4 4013/4885KDM4E 4735/4885ALDH1A1 1816/4885 |
| US-20070015734-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | MAOB, MAOA, GPR119 | IRAK4 2307/4885KDM4E 610/4885ALDH1A1 353/4885 |
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | FAP, FIBP, FGFR1 | IRAK4 692/4885KDM4E 3628/4885ALDH1A1 2246/4885 |
| US-20110015461-A1 | Ionic Liquids for Separation of Olefin-Paraffin Mixtures | POU2F1, POU2F2, POF1B | IRAK4 4013/4885KDM4E 4735/4885ALDH1A1 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.