Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25484165 | 0.88 | NPC1 (0.45) | TSHRMAPK1SMN1; SMN2LCKPOLB | |
| SCHEMBL13609513 | 0.85 | TSHR (0.41) | TSHRMAPK1SMN1; SMN2LCKPOLB | |
| SCHEMBL2718161 | 0.84 | TSHR (0.51) | TSHRSMN1; SMN2LCKGAAALDH1A1 | |
| SCHEMBL2717124 | 0.84 | LCK (0.45) | TSHRMAPK1SMN1; SMN2LCKPOLB | |
| SCHEMBL25484179 | 0.78 | LCK (0.41) | TSHRSMN1; SMN2LCKPI4KBCA1 | |
| SCHEMBL2173294 | 0.77 | LCK (0.54) | LCKPI4KBCA1CA2 | |
| SCHEMBL24434724 | 0.77 | NPC1 (0.55) | LCKPI4KBCA1CA2GAA | |
| SCHEMBL31377270 | 0.76 | SMN1; SMN2 (0.67) | TSHRSMN1; SMN2POLBGAAALDH1A1 | |
| SCHEMBL10840353 | 0.75 | SMN1; SMN2 (0.43) | TSHRMAPK1SMN1; SMN2LCKPOLB | |
| SCHEMBL21222206 | 0.74 | ALDH1A1 (0.62) | TSHRMAPK1SMN1; SMN2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215817-B | 2-aminothiazole-4-acetic acid derivative and preparation method and application thereof | 武汉工程大学 | 2023-09-19 | — | — | CN | disclosed |