Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3045939 | 1.00 | CYP3A4 (0.53) | CYP3A4MEN1KMT2APTGS1DRD3 | |
| Phloroisobutyrophenone SCHEMBL2150396 | 0.79 | FFAR1 (0.68) | CYP3A4MEN1KMT2APTGS1DRD3 | |
| SCHEMBL30550437 | 0.78 | FBP1 (0.56) | CYP3A4MEN1KMT2APTGS1DRD3 | |
| SCHEMBL28598764 | 0.77 | FBP1 (0.55) | CYP3A4MEN1KMT2APTGS1DRD3 | |
| SCHEMBL28604120 | 0.77 | FBP1 (0.55) | CYP3A4MEN1KMT2APTGS1DRD3 | |
| SCHEMBL9407152 | 0.76 | HSP90AB1 (0.58) | CYP3A4MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9407157 | 0.76 | HSP90AB1 (0.58) | CYP3A4MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL457056 | 0.75 | GAA (0.51) | CYP3A4MEN1KMT2AHPGDTDP1 | |
| SCHEMBL17203057 | 0.75 | CYP3A4 (0.52) | CYP3A4MEN1KMT2APTGS1DRD3 | |
| SCHEMBL28603873 | 0.74 | FBP1 (0.52) | CYP3A4MEN1KMT2AFBP1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222426-A1 | Anti-Bacterial Agents | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2010-09-02 | — | — | US | disclosed |
| US-20100222426-A1 | Anti-Bacterial Agents | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2010-09-02 | — | — | US | disclosed |
| US-20100222426-A1 | Anti-Bacterial Agents | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2010-09-02 | — | — | US | disclosed |
| EP-2203404-A2 | ANTI-BACTERIAL AGENTS | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009034346-A2 | ANTI-BACTERIAL AGENTS | SCHOOL OF PHARMACY (GB) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009034346-A2 | ANTI-BACTERIAL AGENTS | SCHOOL OF PHARMACY (GB) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222426-A1 | Anti-Bacterial Agents | B3GNT2, LSS, GNE | CYP3A4 3528/4885MEN1 4090/4885KMT2A 2883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.