Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA7 | P43166 | 4/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407157 | 1.00 | HSP90AB1 (0.58) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL9405591 | 0.87 | HSD17B1 (0.50) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL9405590 | 0.87 | HSD17B1 (0.50) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL12733372 | 0.86 | HSP90AB1 (0.54) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL3559437 | 0.84 | CA12 (0.51) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL9407167 | 0.84 | CA12 (0.44) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL29378476 | 0.81 | CA12 (0.59) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL1830213 | 0.81 | CA12 (0.59) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL28415655 | 0.81 | HSP90AB1 (0.56) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL2989013 | 0.79 | CA12 (0.58) | HSP90AB1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315193-B1 | Optically active compound and chiral liquid crystal composition containing the same | NIPPON TELEGRAPH & TELEPHONE (JP) | 1994-04-06 | — | — | EP | disclosed |
| US-5059345-A | Spontaneous polarization in wide temperature range and high speed response | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1991-10-22 | — | — | US | disclosed |
| EP-0315193-A2 | Optically active compound and chiral liquid crystal composition containing the same | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1989-05-10 | — | — | EP | disclosed |