Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25362939 | 1.00 | PTGS2 (0.40) | PTGS2MAOAMAOBGRM2PTGS1 | |
| SCHEMBL25368100 | 0.93 | HRH3 (0.37) | PTGS2MAOAMAOBGRM2PTGS1 | |
| SCHEMBL30557460 | 0.93 | HRH3 (0.37) | PTGS2MAOAMAOBGRM2PTGS1 | |
| SCHEMBL30557465 | 0.88 | PTGS2 (0.39) | PTGS2MAOAMAOBGRM2PTGS1 | |
| SCHEMBL25364788 | 0.88 | PTGS2 (0.39) | PTGS2MAOAMAOBGRM2PTGS1 | |
| SCHEMBL25366146 | 0.87 | HRH3 (0.47) | PTGS2MAOAMAOBGRM2PTGS1 | |
| SCHEMBL30557377 | 0.87 | HRH3 (0.47) | PTGS2MAOAMAOBGRM2PTGS1 | |
| SCHEMBL25364691 | 0.81 | CYP2D6 (0.40) | PTGS2MAOAMAOBGRM2 | |
| SCHEMBL30557474 | 0.81 | CYP2D6 (0.40) | PTGS2MAOAMAOBGRM2 | |
| SCHEMBL25365541 | 0.80 | PTGS2 (0.39) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479135-A1 | SUBSTITUTED IMIDAZOPYRIDINYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | Bristol-Myers Squibb Company (US) | 2024-12-25 | — | — | EP | disclosed |
| CN-118786130-A | Substituted imidazopyridinyl compounds useful as TLR9 inhibitors | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | disclosed |
| WO-2023159154-A9 | SUBSTITUTED IMIDAZOPYRIDINYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-10-10 | — | — | WO | disclosed |
| WO-2023159154-A1 | SUBSTITUTED IMIDAZOPYRIDINYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-08-24 | — | — | WO | disclosed |