Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | LOX | P28300 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14350330 | 1.00 | HTR6 (0.48) | HTR6HTR2CHTR2BPNMTLOX | |
| SCHEMBL17361961 | 0.88 | GAA (0.43) | HTR6LOXALDH1A1POLBMAPT | |
| SCHEMBL17362253 | 0.87 | HTR6 (0.40) | HTR6LOX | |
| SCHEMBL17361916 | 0.87 | HTR6 (0.53) | HTR6HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL30558349 | 0.86 | GAA (0.42) | HTR6LOXALDH1A1MAPTLOXL2 | |
| Hydrochloric Acid SCHEMBL30558460 | 0.86 | HTR6 (0.39) | HTR6LOX | |
| Hydrochloric Acid SCHEMBL30558373 | 0.86 | HTR6 (0.52) | HTR6HTR2CHTR2B | |
| SCHEMBL19296352 | 0.80 | HTR2C (0.49) | HTR6HTR2CHTR2BPNMTALDH1A1 | |
| SCHEMBL27719897 | 0.78 | HTR2C (0.47) | HTR6HTR2CHTR2BPNMTALDH1A1 | |
| SCHEMBL314648 | 0.77 | HTR2C (0.46) | HTR6HTR2CHTR2BPNMTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909083-B | Inhibitors of histone demethylase | 赛尔基因昆蒂赛尔研究公司 | 2023-08-15 | — | — | CN | disclosed |