Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP19 | O94966 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16462634 | 0.87 | MAOA (0.42) | USP19DPP4DPP7CHRNB2CHRNB4 | |
| SCHEMBL20528485 | 0.86 | DPP4 (0.46) | USP19DPP4DPP7RIPK1HTR2A | |
| SCHEMBL21801033 | 0.86 | DPP4 (0.46) | USP19DPP4DPP7RIPK1HTR2A | |
| SCHEMBL2935422 | 0.86 | DPP4 (0.46) | USP19DPP4DPP7RIPK1HTR2A | |
| Hydrochloric Acid SCHEMBL9258072 | 0.84 | DPP4 (0.46) | USP19DPP4DPP7RIPK1HTR2A | |
| SCHEMBL3314580 | 0.83 | DPP4 (0.53) | DPP4DPP7ALDH1A1MAPTHTR2A | |
| SCHEMBL38659223 | 0.83 | KDM4E (0.45) | USP19CHRNB2CHRNA4CHRNA7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2234958 | 0.82 | USP19 (0.45) | USP19 | |
| SCHEMBL16261916 | 0.82 | DPP4 (0.41) | USP19DPP4DPP7MAOAMAOB | |
| SCHEMBL15636064 | 0.82 | DPP4 (0.41) | USP19DPP4DPP7HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566102-B | Substituted pyrrolopyridines as activin receptor-like kinase inhibitors | 缆图药品公司 | 2023-09-08 | — | — | CN | disclosed |