Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.89 |
| ▸ | BCL3 | P20749 | 5/20 | 0.89 |
| ▸ | GAA | P10253 | 1/20 | 0.89 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17554065 | 1.00 | ALDH1A1 (0.89) | ALDH1A1BCL3GAAPOLBKMT2A | |
| SCHEMBL16430708 | 0.94 | BCL3 (1.00) | ALDH1A1BCL3GAAPOLBKMT2A | |
| SCHEMBL29849945 | 0.94 | BCL3 (1.00) | ALDH1A1BCL3GAAPOLBKMT2A | |
| SCHEMBL30560594 | 0.90 | ALDH1A1 (0.72) | ALDH1A1BCL3GAAPOLBKMT2A | |
| SCHEMBL17554103 | 0.90 | ALDH1A1 (0.72) | ALDH1A1BCL3GAAPOLBKMT2A | |
| SCHEMBL9229341 | 0.87 | POLB (0.84) | ALDH1A1BCL3GAAPOLBKMT2A | |
| SCHEMBL17554144 | 0.87 | ALDH1A1 (0.68) | ALDH1A1BCL3GAAPOLBKMT2A | |
| SCHEMBL10379079 | 0.86 | CYP2C9 (0.73) | ALDH1A1BCL3GAAPOLBCYP2D6 | |
| SCHEMBL17554086 | 0.85 | ALDH1A1 (0.66) | ALDH1A1BCL3GAAPOLBKMT2A | |
| SCHEMBL17554043 | 0.85 | POLB (0.77) | ALDH1A1BCL3GAAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628374-B1 | BCL-3 INHIBITORS | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2023-08-30 | — | — | EP | disclosed |