Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.84 |
| ▸ | BCL3 | P20749 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17554174 | 0.94 | BCL3 (0.76) | POLBBCL3ALDH1A1GAAHTT | |
| SCHEMBL17554065 | 0.87 | ALDH1A1 (0.89) | POLBBCL3ALDH1A1GAAKMT2A | |
| SCHEMBL30560552 | 0.87 | ALDH1A1 (0.89) | POLBBCL3ALDH1A1GAAKMT2A | |
| SCHEMBL17554043 | 0.86 | POLB (0.77) | POLBBCL3ALDH1A1GAAHTT | |
| Eprobemide SCHEMBL570896 | 0.85 | ALDH1A1 (0.85) | ALDH1A1KMT2AHTR1AMAOAMAOB | |
| SCHEMBL16430973 | 0.85 | POLB (0.87) | POLBBCL3ALDH1A1GAAHTT | |
| SCHEMBL29849958 | 0.85 | POLB (0.87) | POLBBCL3ALDH1A1GAAHTT | |
| Eprobemide SCHEMBL10495496 | 0.84 | ALDH1A1 (0.82) | ALDH1A1KMT2AHTR1AMAOAMAOB | |
| SCHEMBL17554128 | 0.83 | BCL3 (1.00) | POLBBCL3ALDH1A1GAAHTT | |
| SCHEMBL17554020 | 0.83 | BCL3 (0.76) | POLBBCL3ALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397798-A | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |