Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16296178 | 1.00 | ALDH1A1 (0.47) | ALDH1A1PGRKDM1AMAOAKDM4E | |
| SCHEMBL16295214 | 0.85 | GAA (0.46) | ALDH1A1KDM4ESLC40A1PKMSLC1A3 | |
| SCHEMBL30560821 | 0.84 | KDM4E (0.43) | KDM4ETSHR | |
| SCHEMBL16296153 | 0.84 | KDM4E (0.43) | KDM4ETSHR | |
| SCHEMBL18065846 | 0.83 | KDM4E (0.49) | KDM4EEDNRAEDNRB | |
| SCHEMBL16295799 | 0.81 | KMT2A (0.49) | ALDH1A1KDM4EPKM | |
| SCHEMBL16295702 | 0.81 | MEN1 (0.56) | ALDH1A1KDM1ASLC40A1 | |
| SCHEMBL16295774 | 0.81 | SLC40A1 (0.46) | ALDH1A1SLC40A1PKM | |
| SCHEMBL30560818 | 0.81 | SLC40A1 (0.46) | ALDH1A1SLC40A1PKM | |
| SCHEMBL30560893 | 0.81 | MEN1 (0.56) | ALDH1A1KDM1ASLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384155-A | Diazabicyclooctanones as serine beta-lactamase inhibitors | 安塔比奥公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-111954671-B | Diazabicyclooctanones as serine beta-lactamase inhibitors | 安塔比奥公司 | 2023-09-01 | — | — | CN | disclosed |