Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 1.00 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3828169 | 0.98 | ALDH1A1 (0.96) | ALDH1A1ATAD2NPC1RAB9APIK3CD | |
| SCHEMBL12680949 | 0.81 | ALDH1A1 (0.69) | ALDH1A1ATAD2NPC1RAB9APIK3CD | |
| SCHEMBL304836 | 0.81 | ALDH1A1 (0.69) | ALDH1A1NPC1RAB9APIK3CDPIK3CA | |
| SCHEMBL4759290 | 0.80 | ALDH1A1 (0.67) | ALDH1A1ATAD2NPC1RAB9APIK3CD | |
| SCHEMBL7173471 | 0.78 | ALDH1A1 (0.64) | ALDH1A1ATAD2NPC1RAB9APIK3CD | |
| SCHEMBL303321 | 0.78 | ATAD2 (1.00) | ALDH1A1ATAD2NPC1RAB9APIK3CD | |
| SCHEMBL16880253 | 0.77 | ALDH1A1 (0.63) | ALDH1A1ATAD2NPC1RAB9APIK3CD | |
| SCHEMBL12680625 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9APIK3CDPIK3CA | |
| SCHEMBL12681554 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9APIK3CDPIK3CA | |
| SCHEMBL12415758 | 0.77 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9APIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9243000-B2 | Thia-triaza-indacenes | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-01-26 | — | — | US | disclosed |
| US-9243000-B2 | Thia-triaza-indacenes | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-01-26 | — | — | US | disclosed |
| US-9243000-B2 | Thia-triaza-indacenes | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-01-26 | — | — | US | disclosed |
| EP-2421872-B1 | THIA-TRIAZA-AS-INDACENES AS PI3-KINASES INHIBITORS FOR THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INT (DE) | 2015-06-10 | — | — | EP | disclosed |
| EP-2421872-B1 | THIA-TRIAZA-AS-INDACENES AS PI3-KINASES INHIBITORS FOR THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INT (DE) | 2015-06-10 | — | — | EP | disclosed |
| US-8273772-B2 | Heteroaryl compounds as P2Y1 receptor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-09-25 | — | — | US | disclosed |
| US-8273772-B2 | Heteroaryl compounds as P2Y1 receptor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-09-25 | — | — | US | disclosed |
| US-20120108618-A1 | THIA-TRIAZA-INDACENES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-03 | — | — | US | disclosed |
| US-20120108618-A1 | THIA-TRIAZA-INDACENES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-03 | — | — | US | disclosed |
| EP-2421872-A1 | THIA-TRIAZA-AS-INDACENES AS PI3-KINASES INHIBITORS FOR THE TREATMENT OF CANCER | Boehringer Ingelheim International GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| EP-1283834-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001090094-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2001-11-29 | — | — | WO | disclosed |
| US-4624698-A | Herbicidal tetrahydrobenzothiazolyl-1,3,5-triazinone derivatives and compositions thereof | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-11-25 | — | — | US | disclosed |
| US-4481027-A | POSTEMERGENCE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-11-06 | — | — | US | disclosed |
| US-4419289-A | YELLOW COLOR FOR POLYESTERS, POLYAMIDES, AND CELLULOSE ESTERS | EASTMAN KODAK COMPANY (US) | 1983-12-06 | — | — | US | disclosed |
| US-4396547-A | INDOLE, THIADIAZOLE AND MONOAZO DYES | EASTMAN KODAK COMPANY (US) | 1983-08-02 | — | — | US | disclosed |
| US-4380640-A | PLANT GROWTH REGULATORS; 7-OXO-BENZOTHIAZOL-2-YL-N-ALKYL UREA DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1983-04-19 | — | — | US | disclosed |
| US-4354970-A | YELLOW TEXTILE DYE | EASTMAN KODAK COMPANY (US) | 1982-10-19 | — | — | US | disclosed |
| EP-0032879-A1 | Benzothiazolyl-urea derivatives, their preparation, formulations containing them and their use as herbicides | CIBA-GEIGY AG (CH) | 1981-07-29 | — | — | EP | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108618-A1 | THIA-TRIAZA-INDACENES | CCNA1, MKI67, CCNT1 | ALDH1A1 51/4885ATAD2 4261/4885NPC1 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.