Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.81 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.81 |
| ▸ | CDC25B | P30305 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1187451 | 1.00 | PTPN1 (0.81) | PTPN1PTPN2CDC25BALOX15MEN1 | |
| SCHEMBL23425674 | 1.00 | PTPN1 (0.81) | PTPN1PTPN2CDC25BALOX15MEN1 | |
| SCHEMBL10295714 | 0.96 | PTPN1 (0.75) | PTPN1PTPN2CDC25BALOX15MEN1 | |
| SCHEMBL3060255 | 0.91 | PTPN1 (0.79) | PTPN1PTPN2CDC25BALOX15MEN1 | |
| SCHEMBL23425635 | 0.91 | PTPN1 (0.79) | PTPN1PTPN2CDC25BALOX15MEN1 | |
| SCHEMBL1187760 | 0.91 | PTPN1 (0.79) | PTPN1PTPN2CDC25BALOX15MEN1 | |
| SCHEMBL3045983 | 0.90 | PTPN1 (0.81) | PTPN1PTPN2CDC25BALOX15MEN1 | |
| SCHEMBL23425627 | 0.90 | PTPN1 (0.81) | PTPN1PTPN2CDC25BALOX15MEN1 | |
| SCHEMBL1187902 | 0.90 | PTPN1 (0.81) | PTPN1PTPN2CDC25BALOX15MEN1 | |
| Vitamin E Quinone SCHEMBL1186492 | 0.89 | PTPN1 (1.00) | PTPN1PTPN2CDC25BALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220055975-A1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | PTC THERAPEUTICS, INC. | 2022-02-24 | — | — | US | disclosed |
| US-11021424-B2 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | PTC THERAPEUTICS, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| EP-2564843-B1 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | BIOELECTRON TECH CORP (US) | 2018-12-26 | — | — | EP | disclosed |
| EP-2471530-B1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | EDISON PHARMACEUTICALS INC (US) | 2017-01-11 | — | — | EP | disclosed |
| EP-2471530-B1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | EDISON PHARMACEUTICALS INC (US) | 2017-01-11 | — | — | EP | disclosed |
| US-9447006-B2 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | EDISON PHARMACEUTICALS, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-9447006-B2 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | EDISON PHARMACEUTICALS, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-9447006-B2 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | EDISON PHARMACEUTICALS, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| EP-1888059-B1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | EDISON PHARMACEUTICALS INC (US) | 2014-12-17 | — | — | EP | disclosed |
| EP-1888059-B1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | EDISON PHARMACEUTICALS INC (US) | 2014-12-17 | — | — | EP | disclosed |
| EP-2564842-A1 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | Edison Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2564843-A1 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | Edison Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2471530-A1 | Redox-active Therapeutics For Treatment Of Mitochondrial Diseases And Other Conditions And Modulation Of Energy Biomarkers | Edison Pharmaceuticals, Inc. (US) | 2012-07-04 | — | — | EP | disclosed |
| US-20100222436-A1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | PTC THERAPEUTICS, INC. | 2010-09-02 | — | — | US | disclosed |
| US-20100222436-A1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | PTC THERAPEUTICS, INC. | 2010-09-02 | — | — | US | disclosed |
| US-20100222436-A1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | PTC THERAPEUTICS, INC. | 2010-09-02 | — | — | US | disclosed |
| US-20060281809-A1 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | PTC THERAPEUTICS, INC. | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281809-A1 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | ECHS1, FH, ACAA2 | PTPN1 4752/4885PTPN2 4795/4885CDC25B 4590/4885 |
| US-20100222436-A1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | ECHS1, FH, ACAA2 | PTPN1 4752/4885PTPN2 4795/4885CDC25B 4590/4885 |
| US-11021424-B2 | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers | ECHS1, FH, ACAA2 | PTPN1 4752/4885PTPN2 4795/4885CDC25B 4590/4885 |
| US-20220055975-A1 | REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS | ECHS1, FH, ACAA2 | PTPN1 4752/4885PTPN2 4795/4885CDC25B 4590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.