Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.62 |
| ▸ | MAOB | P27338 | 6/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041636 | 0.93 | MAOA (0.53) | MAOAMAOBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL28532774 | 0.84 | MAOB (0.63) | MAOAMAOBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29711788 | 0.84 | MAOB (0.63) | MAOAMAOBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL14865958 | 0.84 | MAOB (0.63) | MAOAMAOBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL16339494 | 0.82 | CYP11B1 (0.57) | CYP19A1CYP11B1CYP11B2KMT2A | |
| SCHEMBL16537757 | 0.82 | PDE4A (0.53) | MAOAMAOBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL16536586 | 0.82 | PDE4A (0.53) | MAOAMAOBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6031474 | 0.81 | EGFR (0.50) | CHRNA7PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL5762667 | 0.80 | CHRNA7 (0.55) | CHRNA7PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4814842 | 0.78 | CHRNA7 (0.56) | MAOAMAOBCHRNA7PDE4BCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | MAOA 2205/4885MAOB 1395/4885CYP19A1 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.