Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340281 | 0.89 | CYP19A1 (0.48) | CYP11B1CYP11B2CYP19A1SRCEGFR | |
| SCHEMBL7429093 | 0.89 | CYP19A1 (0.48) | CYP11B1CYP11B2CYP19A1SRCEGFR | |
| SCHEMBL16339815 | 0.89 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1CA9CYP1A2 | |
| SCHEMBL3309794 | 0.86 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1CA9CYP1A2 | |
| SCHEMBL10572961 | 0.86 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP19A1CA9CYP1A2 | |
| SCHEMBL28398373 | 0.86 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP19A1CA9CYP1A2 | |
| SCHEMBL2203230 | 0.86 | CA9 (0.50) | CYP11B1CYP11B2CYP19A1CA9CYP1A2 | |
| SCHEMBL6073613 | 0.84 | ALDH1A1 (0.47) | CYP11B1CYP11B2CYP19A1CA9CYP1A2 | |
| SCHEMBL578508 | 0.83 | SRC (0.57) | PDE3BPDE3ASRCEGFRCYP3A4 | |
| SCHEMBL8359848 | 0.82 | CYP11B1 (0.46) | CYP11B1CYP11B2CYP19A1CA9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587239-B | Method for producing lactam compound and lactam compound produced by the method | 基础科学研究院 | 2024-04-02 | — | — | CN | disclosed |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | INSTITUTE FOR BASIC SCIENCE (KR) | 2021-06-29 | — | — | US | disclosed |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | INSTITUTE FOR BASIC SCIENCE (KR) | 2021-06-29 | — | — | US | disclosed |
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | INSTITUTE FOR BASIC SCIENCE (KR) | 2020-10-22 | — | — | US | disclosed |
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | INSTITUTE FOR BASIC SCIENCE (KR) | 2020-10-22 | — | — | US | disclosed |
| CN-111587239-A | Method for producing lactam compound and lactam compound produced by same | 基础科学研究院 | 2020-08-25 | — | — | CN | disclosed |
| WO-2019135604-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |
| CN-105658650-B | imidazole compounds as modulators of follicle stimulating hormone receptors and uses thereof | 默克专利有限公司 | 2019-01-08 | — | — | CN | disclosed |
| US-10138233-B2 | Imidazole compounds as modulators of FSHR and uses thereof | MERCK PATENT GMBH (DE) | 2018-11-27 | — | — | US | disclosed |
| EP-3013823-B1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| EP-3013823-B1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-9725465-B2 | Biaryl acetamide compounds and methods of use thereof | AMBIT BIOSCIENCES CORPORATION (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160152609-A1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-06-02 | — | — | US | disclosed |
| US-20160152609-A1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-06-02 | — | — | US | disclosed |
| US-20160152609-A1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2016-06-02 | — | — | US | disclosed |
| EP-3013823-A1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | Merck Patent GmbH (DE) | 2016-05-04 | — | — | EP | disclosed |
| US-20150065468-A1 | BIARYL ACETAMIDE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORP (US) | 2015-03-05 | — | — | US | disclosed |
| WO-2014209978-A1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014209978-A1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2014-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | SQLE, COASY, DHPS | CYP11B1 1018/4885CYP11B2 809/4885CYP19A1 99/4885 |
| US-20150065468-A1 | BIARYL ACETAMIDE COMPOUNDS AND METHODS OF USE THEREOF | ERBB2, ERBB3, AADAC | CYP11B1 843/4885CYP11B2 580/4885CYP19A1 874/4885 |
| US-10138233-B2 | Imidazole compounds as modulators of FSHR and uses thereof | FSHR, GNRHR, LHCGR | CYP11B1 249/4885CYP11B2 305/4885CYP19A1 17/4885 |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | SQLE, COASY, DHPS | CYP11B1 1018/4885CYP11B2 809/4885CYP19A1 99/4885 |
| US-20160152609-A1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | FSHR, GNRHR, LHCGR | CYP11B1 249/4885CYP11B2 305/4885CYP19A1 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.