Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30481297 | 0.78 | PDE3B (0.32) | — | |
| SCHEMBL17103960 | 0.78 | — | — | |
| SCHEMBL25273956 | 0.78 | PDE3B (0.32) | — | |
| SCHEMBL13791331 | 0.77 | HTR2C (0.33) | — | |
| SCHEMBL30834466 | 0.73 | TRPA1 (0.44) | — | |
| SCHEMBL16246590 | 0.73 | TRPA1 (0.44) | — | |
| SCHEMBL30564256 | 0.73 | ALOX5AP (0.36) | — | |
| SCHEMBL28504175 | 0.70 | CHRNB4 (0.30) | — | |
| SCHEMBL18524116 | 0.70 | — | — | |
| SCHEMBL15055780 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742543-A | Dihydro isoquinoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-10-01 | — | — | CN | disclosed |
| WO-2023174383-A1 | DIHYDROISOQUINOLINE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-09-21 | — | — | WO | disclosed |