Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.70 |
| ▸ | AKR1C2 | P52895 | 9/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CDC42 | P60953 | 1/20 | 0.49 |
| ▸ | RAC1 | P63000 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1492942 | 1.00 | AKR1C3 (0.70) | AKR1C3AKR1C2AKR1B1ALDH1A1LMNA | |
| SCHEMBL2341919 | 1.00 | AKR1C3 (0.70) | AKR1C3AKR1C2AKR1B1ALDH1A1LMNA | |
| SCHEMBL28169181 | 0.89 | AKR1C3 (0.57) | AKR1C3AKR1C2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30564459 | 0.88 | AKR1C3 (0.60) | AKR1C3AKR1C2AKR1B1ALDH1A1PTGS1 | |
| SCHEMBL9910479 | 0.86 | AKR1C3 (0.55) | AKR1C3AKR1C2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30314473 | 0.86 | AKR1C3 (0.55) | AKR1C3AKR1C2ALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2696415 | 0.85 | AKR1C3 (0.54) | AKR1C3AKR1C2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1669333 | 0.84 | ALOX15 (0.57) | AKR1C3AKR1C2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27755472 | 0.82 | AKR1C3 (0.55) | AKR1C3AKR1C2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3594072 | 0.82 | AKR1C3 (0.52) | AKR1C3AKR1C2ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406007-A | Synthesis method of 3- (quinoline-6-yl) propionic acid | 上海毕得医药科技股份有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-118406007-A | Synthesis method of 3- (quinoline-6-yl) propionic acid | 上海毕得医药科技股份有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-118406007-A | Synthesis method of 3- (quinoline-6-yl) propionic acid | 上海毕得医药科技股份有限公司 | 2024-07-30 | — | — | CN | disclosed |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | AKR1C3 4578/4885AKR1C2 4274/4885AKR1B1 4239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.