Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459320 | 1.00 | NPSR1 (0.58) | NPSR1RECQLTSHRHTTUSP2 | |
| SCHEMBL3047693 | 0.87 | GLA (0.52) | TSHRUSP2MMP13HPGDKMT2A | |
| SCHEMBL30565171 | 0.84 | SMN1; SMN2 (0.54) | HTTMMP13KMT2AALDH1A1MAPT | |
| SCHEMBL4194312 | 0.83 | VNN1 (0.62) | NPSR1RECQLTSHRHTTUSP2 | |
| SCHEMBL31185460 | 0.83 | VNN1 (0.62) | NPSR1RECQLTSHRHTTUSP2 | |
| SCHEMBL30565173 | 0.81 | WDR5 (0.43) | TSHRHTTMMP13HPGDKMT2A | |
| SCHEMBL1588305 | 0.79 | RECQL (0.60) | NPSR1RECQLTSHRHTTUSP2 | |
| SCHEMBL14625755 | 0.78 | NPSR1 (0.56) | NPSR1RECQLTSHRHTTUSP2 | |
| SCHEMBL7082686 | 0.77 | TSHR (0.73) | NPSR1RECQLTSHRHTTUSP2 | |
| SCHEMBL4203321 | 0.77 | HPGD (0.59) | HTTHPGDKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452245-A1 | COMBINATION OF AN ALPHA 2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS WITH A MUSCARINIC RECEPTOR ANTAGONIST FOR THE TREATMENT OF SLEEP APNEA | Bayer Aktiengesellschaft (DE) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023118098-A1 | COMBINATION OF AN α2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS WITH A MUSCARINIC RECEPTOR ANTAGONIST FOR THE TREATMENT OF SLEEP APNEA | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-29 | — | — | WO | disclosed |