SCHEMBL30565294

SCHEMBL30565294

Nc1ccccc1C=Cc1ccc(F)cc1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 13/20 0.66
SNCA P37840 1/20 0.46
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
CYP19A1 P11511 1/20 0.43
RELA Q04206 1/20 0.43
APP P05067 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11301695 0.89 CYP19A1 (0.52) NFE2L2MAOAMAOBCYP19A1RELA
SCHEMBL2776707 0.83 CYP19A1 (0.64) NFE2L2MAOAMAOBCYP19A1APP
SCHEMBL2776715 0.83 CYP19A1 (0.64) NFE2L2MAOAMAOBCYP19A1APP
(Z)-1,2-Diphenylethene SCHEMBL28164872 0.83 MAOB (0.56) NFE2L2MAOAMAOBCYP19A1
SCHEMBL3885086 0.83 MAOB (0.56) NFE2L2MAOAMAOBCYP19A1
SCHEMBL29397541 0.83 MAOB (0.56) NFE2L2MAOAMAOBCYP19A1
SCHEMBL5431188 0.83 MAOB (0.56) NFE2L2MAOAMAOBCYP19A1
SCHEMBL911942 0.83 MAOB (0.56) NFE2L2MAOAMAOBCYP19A1
SCHEMBL28876217 0.82 NFE2L2 (0.47) NFE2L2SNCA
SCHEMBL10701354 0.81 MAOB (0.54) NFE2L2MAOAMAOBCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116786165-A Controllable oxidative dehydrogenation coupling method for catalyzing aniline by using low-valence tungsten 江苏科技大学 2023-09-22 CN disclosed