Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17377038 | 1.00 | L3MBTL1 (0.51) | L3MBTL1PARP1MPOKDM4EMAPT | |
| SCHEMBL22331488 | 0.85 | L3MBTL1 (0.49) | L3MBTL1PARP1MPOKDM4EMAPT | |
| SCHEMBL3371229 | 0.85 | BRD4 (0.53) | KDM4ECYP1A2BRD4HTTALDH1A1 | |
| SCHEMBL11509008 | 0.82 | KDM4E (0.46) | L3MBTL1KDM4EMAPTCYP1A2ALOX15 | |
| SCHEMBL535668 | 0.82 | L3MBTL1 (0.58) | L3MBTL1PARP1MPOKDM4EMAPT | |
| SCHEMBL21678221 | 0.81 | L3MBTL1 (0.54) | L3MBTL1PARP1MPOKDM4EMAPT | |
| SCHEMBL9206623 | 0.81 | KDM4E (0.62) | L3MBTL1KDM4EMAPTCYP1A2ALOX15 | |
| SCHEMBL28677368 | 0.81 | L3MBTL1 (0.57) | L3MBTL1PARP1MPOKDM4EMAPT | |
| SCHEMBL25414723 | 0.80 | L3MBTL1 (0.55) | L3MBTL1PARP1MPOKDM4EMAPT | |
| SCHEMBL128967 | 0.80 | L3MBTL1 (0.55) | L3MBTL1PARP1MPOKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583501-A | Compounds and compositions for treating conditions associated with LPA receptor activity | 罗特斯生物公司 | 2023-08-11 | — | — | CN | disclosed |