Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29918474 | 0.76 | GPR119 (0.50) | GPR119KDM4EMAPTTHRBPTPN2 | |
| SCHEMBL693588 | 0.76 | FAAH (0.41) | ELANEGPR119USP30USP2 | |
| SCHEMBL20528595 | 0.74 | ELANE (0.34) | ELANEGPR119USP30 | |
| SCHEMBL20449149 | 0.74 | ELANE (0.34) | ELANEGPR119USP30 | |
| SCHEMBL20449148 | 0.74 | ELANE (0.34) | ELANEGPR119USP30 | |
| SCHEMBL22951279 | 0.74 | FAAH (0.40) | ELANEGPR119USP30USP2 | |
| SCHEMBL22501848 | 0.74 | ELANE (0.44) | ELANEGPR119USP30USP2 | |
| SCHEMBL1864917 | 0.74 | FAAH (0.40) | ELANEGPR119USP30USP2 | |
| SCHEMBL2489522 | 0.74 | ELANE (0.39) | ELANEGPR119KDM4EMAPTTHRB | |
| SCHEMBL27153822 | 0.73 | KRAS (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843642-A | Difunctional compound and application thereof | 麦科萨药业(苏州)有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-116685326-A | Co-crystals of CDK inhibitors | 奥瑞珍肿瘤有限公司 | 2023-09-01 | — | — | CN | disclosed |