SCHEMBL30565867

SCHEMBL30565867

O=S(=O)(c1ccccn1)C(F)Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.47
KDM4E B2RXH2 2/20 0.47
NFE2L2 Q16236 4/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KEAP1 Q14145 1/20 0.39
SLC40A1 Q9NP59 3/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
LOX P28300 1/20 0.37
GLO1 Q04760 1/20 0.37
KAT6A Q92794 1/20 0.37
TXNRD1 Q16881 1/20 0.37
TRPV4 Q9HBA0 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
POLB P06746 3/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
THRB P10828 1/20 0.35
MAPK1 P28482 1/20 0.35
SLC6A2 P23975 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18322824 0.84 KDM4E (0.46) PKMKDM4ENFE2L2L3MBTL1KEAP1
SCHEMBL29707064 0.84 KDM4E (0.46) PKMKDM4ENFE2L2L3MBTL1KEAP1
SCHEMBL30358629 0.81 KDM4E (0.43) PKMKDM4ENFE2L2L3MBTL1KEAP1
SCHEMBL30565846 0.81 KDM4E (0.43) PKMKDM4ENFE2L2L3MBTL1SLC40A1
SCHEMBL28925088 0.78 KDM4E (0.41) PKMKDM4ENFE2L2L3MBTL1KEAP1
SCHEMBL28640674 0.78 SLC6A2 (0.44) PKMKDM4ENFE2L2L3MBTL1SLC40A1
SCHEMBL25379583 0.77 KAT6A (0.43) PKMKDM4ENFE2L2L3MBTL1SLC40A1
SCHEMBL819454 0.76 KDM4E (0.46) PKMKDM4ENFE2L2L3MBTL1KEAP1
SCHEMBL30565843 0.75 MAOA (0.40) PKMKDM4ENFE2L2L3MBTL1SLC40A1
SCHEMBL11470842 0.75 PKM (0.42) PKMKDM4ENFE2L2L3MBTL1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116710467-A Photooxidation reduction protein modification 罗莎琳德·富兰克林研究所 2023-09-05 CN disclosed