Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12820628 | 1.00 | PDE3B (0.51) | PDE3BPDE3AHSD17B10NAMPTMAPT | |
| SCHEMBL985935 | 0.85 | HSD17B10 (0.57) | PDE3BPDE3AHSD17B10MAPTAKT1 | |
| SCHEMBL25780156 | 0.84 | HSD17B10 (0.56) | PDE3BPDE3AHSD17B10MAPTAKT1 | |
| SCHEMBL3383472 | 0.84 | HSD17B10 (0.58) | PDE3BPDE3AHSD17B10MAPTMAPK1 | |
| SCHEMBL28734074 | 0.83 | HSD17B10 (0.48) | HSD17B10NAMPTMAPTLMNAALDH1A1 | |
| SCHEMBL3378290 | 0.83 | AKT1 (0.62) | PDE3BPDE3AHSD17B10MAPTAKT1 | |
| SCHEMBL25780858 | 0.82 | HSD17B10 (0.54) | PDE3BPDE3AHSD17B10MAPTAKT1 | |
| SCHEMBL25780664 | 0.82 | HSD17B10 (0.56) | PDE3BPDE3AHSD17B10MAPTAKT1 | |
| SCHEMBL28734098 | 0.82 | MAP4K4 (0.49) | PDE3BPDE3AHSD17B10NAMPTMAPT | |
| SCHEMBL20293286 | 0.82 | HSD17B10 (0.53) | PDE3BPDE3AHSD17B10MAPTAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214287-B | HPK1 inhibitors and methods of use thereof | 大学健康网络 | 2023-10-20 | — | — | CN | disclosed |