Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13041553 | 0.85 | HSD17B10 (0.54) | HSD17B10TLR9TLR8TLR7ALDH1A1 | |
| SCHEMBL12820628 | 0.83 | PDE3B (0.51) | HSD17B10GPR119ALDH1A1MEN1LMNA | |
| SCHEMBL30565902 | 0.83 | PDE3B (0.51) | HSD17B10GPR119ALDH1A1MEN1LMNA | |
| SCHEMBL25779773 | 0.83 | TRPV3 (0.45) | HSD17B10TP53POLBALDH1A1MEN1 | |
| SCHEMBL30592552 | 0.80 | HSD17B10 (0.47) | HSD17B10CHEK2ALDH1A1MEN1LMNA | |
| SCHEMBL30592547 | 0.80 | HSD17B10 (0.47) | HSD17B10CHEK2ALDH1A1MEN1LMNA | |
| SCHEMBL28734077 | 0.80 | ALDH1A1 (0.43) | HSD17B10TP53POLBALDH1A1MEN1 | |
| SCHEMBL14711416 | 0.78 | GPR119 (0.52) | GPR119TP53POLBALDH1A1MEN1 | |
| SCHEMBL24320252 | 0.77 | DPP4 (0.53) | GPR119TLR7TP53POLBPDE4B | |
| SCHEMBL17092664 | 0.76 | PIK3CA (0.51) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721620-B | HPK1 inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-05-13 | — | — | CN | disclosed |