Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25385840 | 1.00 | RXFP1 (0.53) | RXFP1L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL30567126 | 0.90 | RXFP1 (0.47) | RXFP1L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL25386208 | 0.90 | RXFP1 (0.47) | RXFP1L3MBTL1HTTKMT2AMEN1 | |
| SCHEMBL30567121 | 0.87 | MAPK1 (0.46) | L3MBTL1KMT2AMEN1ALDH1A1BLM | |
| SCHEMBL25386759 | 0.87 | MAPK1 (0.46) | L3MBTL1KMT2AMEN1ALDH1A1BLM | |
| SCHEMBL25386145 | 0.87 | ALDH1A1 (0.54) | L3MBTL1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL31256612 | 0.87 | ALDH1A1 (0.54) | L3MBTL1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL25387819 | 0.83 | MAPK1 (0.53) | L3MBTL1KMT2AMEN1ALDH1A1BLM | |
| SCHEMBL30567110 | 0.83 | MAPK1 (0.53) | L3MBTL1KMT2AMEN1ALDH1A1BLM | |
| SCHEMBL25388664 | 0.83 | POLB (0.49) | L3MBTL1KMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4490142-A2 | PCNA INHIBITORS AND USES THEREOF | City of Hope (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2023172880-A2 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2023-09-14 | — | — | WO | disclosed |