Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25386208 | 1.00 | RXFP1 (0.47) | RXFP1TAOK1ALDH1A1BLMLMNA | |
| SCHEMBL30567207 | 0.90 | RXFP1 (0.53) | RXFP1ALDH1A1BLMLMNAKMT2A | |
| SCHEMBL25385840 | 0.90 | RXFP1 (0.53) | RXFP1ALDH1A1BLMLMNAKMT2A | |
| SCHEMBL30567110 | 0.89 | MAPK1 (0.53) | TAOK1ALDH1A1BLMLMNANPSR1 | |
| SCHEMBL25387819 | 0.89 | MAPK1 (0.53) | TAOK1ALDH1A1BLMLMNANPSR1 | |
| SCHEMBL25386145 | 0.88 | ALDH1A1 (0.54) | TAOK1ALDH1A1BLMLMNANPSR1 | |
| SCHEMBL31256612 | 0.88 | ALDH1A1 (0.54) | TAOK1ALDH1A1BLMLMNANPSR1 | |
| SCHEMBL25386852 | 0.87 | L3MBTL1 (0.50) | TAOK1ALDH1A1BLMLMNANPSR1 | |
| SCHEMBL25386759 | 0.83 | MAPK1 (0.46) | TAOK1ALDH1A1BLMLMNANPSR1 | |
| SCHEMBL30567121 | 0.83 | MAPK1 (0.46) | TAOK1ALDH1A1BLMLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4490142-A2 | PCNA INHIBITORS AND USES THEREOF | City of Hope (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2023172880-A2 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2023-09-14 | — | — | WO | disclosed |