SCHEMBL30567690

CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(C)C)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)O)[C@@H](C)O

nearest known ligand 0.67

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	8/20	0.62

▸	NPY4R	P50391	8/20	0.62

▸	NPY5R	Q15761	8/20	0.62

▸	NPY1R	P25929	7/20	0.62

▸	EP300	Q09472	1/20	0.58

▸	HIF1A	Q16665	1/20	0.58

▸	MAPK8	P45983	1/20	0.58

▸	MAPK9	P45984	1/20	0.58

▸	MAPK10	P53779	1/20	0.58

▸	NTSR2	O95665	2/20	0.56

▸	NTSR1	P30989	2/20	0.56

▸	SORT1	Q99523	2/20	0.56

▸	VIPR1	P32241	2/20	0.55

▸	KDM1A	O60341	1/20	0.55

▸	VIPR2	P41587	1/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31182927	0.91	NPY2R (0.71)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30608553	0.88	NPY2R (0.68)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30835683	0.87	NPY2R (0.62)	NPY2RNPY4RNPY5RNPY1RMAPK8
Oncocin SCHEMBL29538886	0.87	KDM1A (0.62)	NPY2RNPY4RNPY5RNPY1RKDM1A
SCHEMBL31738531	0.87	NTSR1 (0.66)	NPY2RNPY4RNPY5RNPY1RNTSR2
SCHEMBL31548697	0.87	NTSR1 (0.66)	NPY2RNPY4RNPY5RNPY1RNTSR2
SCHEMBL29855986	0.87	NPY2R (0.66)	NPY2RNPY4RNPY5RNPY1RKDM1A
SCHEMBL29903370	0.87	NPY2R (0.64)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL30607456	0.87	NPY2R (0.70)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30567697	0.87	NPY2R (0.65)	NPY2RNPY4RNPY5RNPY1REP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240277841-A2	HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE	NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT	2024-08-22	—	—	US	disclosed
US-20240024473-A1	HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE	PURDUE RESEARCH FOUNDATION (US)	2024-01-25	—	—	US	disclosed
CN-116601290-A	Human chimeric antigen receptor neutrophils, compositions, kits and methods of use	普渡研究基金会	2023-08-15	—	—	CN	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20240277841-A2	HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE	PBK, KIT, MYD88	NPY2R 3831/4885NPY4R 3873/4885NPY5R 3302/4885
US-20240024473-A1	HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE	PBK, KIT, MYD88	NPY2R 3831/4885NPY4R 3873/4885NPY5R 3302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.