Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 9/20 | 0.66 |
| ▸ | NPY1R | P25929 | 9/20 | 0.66 |
| ▸ | NPY4R | P50391 | 8/20 | 0.66 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.66 |
| ▸ | EP300 | Q09472 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | RAMP3 | O60896 | 4/20 | 0.57 |
| ▸ | CALCR | P30988 | 4/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.54 |
| ▸ | RAMP2 | O60895 | 1/20 | 0.54 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.54 |
| ▸ | GLP1R | P43220 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30607358 | 0.88 | NPY2R (0.69) | NPY2RNPY1RNPY4RNPY5REP300 | |
| SCHEMBL29903278 | 0.88 | NPY2R (0.63) | NPY2RNPY1RNPY4RNPY5REP300 | |
| SCHEMBL31182927 | 0.87 | NPY2R (0.71) | NPY2RNPY1RNPY4RNPY5REP300 | |
| SCHEMBL30176436 | 0.87 | NPY2R (0.68) | NPY2RNPY1RNPY4RNPY5RRAMP3 | |
| SCHEMBL31005063 | 0.87 | NPY2R (0.62) | NPY2RNPY1RNPY4RNPY5REP300 | |
| SCHEMBL31005056 | 0.86 | NPY2R (0.64) | NPY2RNPY1RNPY4RNPY5REP300 | |
| SCHEMBL30887559 | 0.86 | MAPK8 (0.62) | NPY2RNPY1RNPY4RNPY5REP300 | |
| SCHEMBL30607456 | 0.85 | NPY2R (0.70) | NPY2RNPY1RNPY4RNPY5REP300 | |
| SCHEMBL30320527 | 0.85 | NPY2R (0.65) | NPY2RNPY1RNPY4RNPY5REP300 | |
| SCHEMBL11150031 | 0.85 | NPY2R (0.73) | NPY2RNPY1RNPY4RNPY5REP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240277841-A2 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-08-22 | — | — | US | disclosed |
| US-20240024473-A1 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PURDUE RESEARCH FOUNDATION (US) | 2024-01-25 | — | — | US | disclosed |
| CN-116601290-A | Human chimeric antigen receptor neutrophils, compositions, kits and methods of use | 普渡研究基金会 | 2023-08-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240277841-A2 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PBK, KIT, MYD88 | NPY2R 3831/4885NPY1R 2969/4885NPY4R 3873/4885 |
| US-20240024473-A1 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PBK, KIT, MYD88 | NPY2R 3831/4885NPY1R 2969/4885NPY4R 3873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.